Disulfiram-alcohol reaction
Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some mushrooms. The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine use). Once disulfiram-treated patients take alcohol, even in small doses, they experience strong unpleasant sensations (flush, nausea, lightheadedness, headache, sweating, vomiting, and vertigo).
| Disulfiram-alcohol reaction (DAR) | |
|---|---|
| Other names | Disulfiram ethanol reaction (DER), Antabuse effect, Acetylhyde sindrome |
| Alcohol flush reaction is a visible effect of DAR. | |
| Specialty | Toxicology |
| Symptoms | Flush, nausea, lightheadedness, headache, sweating, vomiting, vertigo, etc |
| Causes | Ingestion of disulfiram with alcohol |
Disulfiram has been used to treat alcoholism since 1948 after its accidental discovery in Denmark.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.