Dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a condition in which the heart becomes enlarged and cannot pump blood effectively. Symptoms vary from none to feeling tired, leg swelling, and shortness of breath. It may also result in chest pain or fainting. Complications can include heart failure, heart valve disease, or an irregular heartbeat.

Dilated cardiomyopathy
Other namesCongestive cardiomyopathy,
idiopathic cardiomyopathy,
primary cardiomyopathy
Mouse heart slice showing dilated cardiomyopathy
SpecialtyCardiology
SymptomsFeeling tired, leg swelling, shortness of breath, chest pain, fainting
ComplicationsHeart failure, heart valve disease, irregular heartbeat
Usual onsetMiddle age
TypesTachycardia-induced, others
CausesGenetics, alcohol, cocaine, certain toxins, complications of pregnancy, in many cases the cause remains unclear, certain infections
Diagnostic methodSupported by electrocardiogram, chest X-ray, echocardiogram
Differential diagnosisCoronary artery disease, heart valve disease, pulmonary embolism, other cardiomyopathy
TreatmentLifestyle changes, medications, implantable cardioverter defibrillator, cardiac resynchronization therapy (CRT), heart transplant
MedicationACE inhibitor, beta blocker, diuretic, blood thinners
PrognosisFive-year survival rate ~50%
Frequency1 in 2500

Causes include genetics, alcohol, cocaine, certain toxins, complications of pregnancy, and certain infections. Coronary artery disease and high blood pressure may play a role, but are not the primary cause. In many cases the cause remains unclear. It is a type of cardiomyopathy, a group of diseases that primarily affects the heart muscle. The diagnosis may be supported by an electrocardiogram, chest X-ray, or echocardiogram.

In those with heart failure, treatment may include medications in the ACE inhibitor, beta blocker, and diuretic families. A low salt diet may also be helpful. In those with certain types of irregular heartbeat, blood thinners or an implantable cardioverter defibrillator may be recommended. Cardiac resynchronization therapy (CRT) may be necessary. If other measures are not effective a heart transplant may be an option in some.

About 1 per 2,500 people is affected. It occurs more frequently in men than women. Onset is most often in middle age. Five-year survival rate is about 50%. It can also occur in children and is the most common type of cardiomyopathy in this age group.

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