Delta endotoxins
Delta endotoxins (δ-endotoxins) are a family of pore-forming toxins produced by Bacillus thuringiensis species of bacteria. They are useful for their insecticidal action and are the primary toxin produced by the genetically modified (GM) Bt maize/corn and other GM crops. During spore formation the bacteria produce crystals of such proteins (hence the name Cry toxins) that are also known as parasporal bodies, next to the endospores; as a result some members are known as a parasporin. The Cyt (cytolytic) toxin group is another group of delta-endotoxins formed in the cytoplasm. VIP toxins (vegetative insecticidal proteins) are formed at other stages of the life cycle.
Delta endotoxin, N-terminal domain | |||||||||
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crystal structure of the insecticidal bacterial del endotoxin Cry3Bb1 Bacillus thuringiensis | |||||||||
Identifiers | |||||||||
Symbol | Endotoxin_N | ||||||||
Pfam | PF03945 | ||||||||
InterPro | IPR005639 | ||||||||
SCOP2 | 1dlc / SCOPe / SUPFAM | ||||||||
TCDB | 1.C.2 | ||||||||
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Delta endotoxin, middle domain | |||||||||
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Identifiers | |||||||||
Symbol | Endotoxin_M | ||||||||
Pfam | PF00555 | ||||||||
Pfam clan | CL0568 | ||||||||
InterPro | IPR015790 | ||||||||
SCOP2 | 1dlc / SCOPe / SUPFAM | ||||||||
TCDB | 1.C.2 | ||||||||
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Delta endotoxin, middle domain, Cry2A and Cry18 | |||||||||
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insecticidal crystal protein cry2aa | |||||||||
Identifiers | |||||||||
Symbol | Endotoxin_mid | ||||||||
Pfam | PF09131 | ||||||||
InterPro | IPR015214 | ||||||||
SCOP2 | 1i5p / SCOPe / SUPFAM | ||||||||
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Delta endotoxin, C-terminal | |||||||||
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Identifiers | |||||||||
Symbol | Endotoxin_C | ||||||||
Pfam | PF03944 | ||||||||
Pfam clan | CL0202 | ||||||||
InterPro | IPR005638 | ||||||||
SCOP2 | 1dlc / SCOPe / SUPFAM | ||||||||
TCDB | 1.C.2 | ||||||||
CDD | cd04085 | ||||||||
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Cytolytic delta-endotoxin Cyt1/2 | |||||||||
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Identifiers | |||||||||
Symbol | CytB | ||||||||
Pfam | PF01338 | ||||||||
InterPro | IPR001615 | ||||||||
SCOP2 | 1cby / SCOPe / SUPFAM | ||||||||
TCDB | 1.C.71 | ||||||||
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