Aromatic L-amino acid decarboxylase
Aromatic L-amino acid decarboxylase (AADC or AAAD), also known as DOPA decarboxylase (DDC), tryptophan decarboxylase, and 5-hydroxytryptophan decarboxylase, is a lyase enzyme (EC 4.1.1.28), located in region 7p12.2-p12.1.
| Aromatic L amino acid decarboxylase (DOPA decarboxylase) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Ribbon diagram of a DOPA decarboxylase dimer. | |||||||||
| Identifiers | |||||||||
| EC no. | 4.1.1.28 | ||||||||
| CAS no. | 9042-64-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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| DOPA decarboxylase (aromatic L-amino acid decarboxylase) | |||||||
|---|---|---|---|---|---|---|---|
Aromatic L-amino acid decarboxylase homodimer, Human | |||||||
| Identifiers | |||||||
| Symbol | DDC | ||||||
| NCBI gene | 1644 | ||||||
| HGNC | 2719 | ||||||
| OMIM | 107930 | ||||||
| RefSeq | NM_000790 | ||||||
| UniProt | P20711 | ||||||
| Other data | |||||||
| EC number | 4.1.1.28 | ||||||
| Locus | Chr. 7 p11 | ||||||
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