DLX6

DLX6
Identifiers
Aliases	DLX6, distal-less homeobox 6
External IDs	OMIM: 600030 MGI: 101927 HomoloGene: 87855 GeneCards: DLX6
Gene location (Human)
Chr.	Chromosome 7 (human)
End	97,011,040 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	6,868,568 bp
RNA expression pattern
	Top expressed in
	endometrium; ; nucleus accumbens; ; caudate nucleus; ; putamen; ; oocyte; ; sperm; ; endothelial cell; ; placenta; ; Achilles tendon; ; external globus pallidus;
	Top expressed in
	superior frontal gyrus; ; medial ganglionic eminence; ; olfactory tubercle; ; olfactory bulb; ; spermatid; ; cervical loop; ; tongue; ; enteric nervous system; ; pharynx; ; globus pallidus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	nucleus;
Biological process	skeletal system development; regulation of transcription, DNA-templated; nervous system development; embryonic limb morphogenesis; epithelial cell differentiation; inner ear morphogenesis; anatomical structure formation involved in morphogenesis; positive regulation of epithelial cell proliferation; roof of mouth development; head development; multicellular organism development; regulation of transcription by RNA polymerase II; cell differentiation; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	1750
	13396
	ENSG00000006377
	ENSMUSG00000029754
	P56179
	P70397
	NM_005222
	NM_010057
	NP_005213
	NP_034187
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein DLX-6 is a protein that in humans is encoded by the DLX6 gene.

This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene. This family has at least six members that encode proteins with roles in forebrain and craniofacial development. This gene is in a tail-to-tail configuration with another member of the family, DLX5, on the long arm of chromosome 7.

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