D-DOPA
d-DOPA (d-3,4-dihydroxyphenylalanine; dextrodopa) is similar to l-DOPA (levodopa), but with opposite chirality. Levo- and dextro- rotation refer to a molecule's ability to rotate planes of polarized light in one or the other direction. Whereas l-DOPA is moderately effective in the treatment of Parkinson's disease (PD) and dopamine-responsive dystonia (DRD) by stimulating the production of dopamine in the brain, d-DOPA is biologically inactive.
Names | |
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IUPAC name
3,4-Dihydroxy-D-phenylalanine | |
Systematic IUPAC name
(2R)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid | |
Identifiers | |
3D model (JSmol) |
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ChemSpider | |
ECHA InfoCard | 100.024.858 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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SMILES
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Properties | |
C9H11NO4 | |
Molar mass | 197.19 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |
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