Cyclin-dependent kinase inhibitor 1C

CDKN1C
Identifiers
Aliases	CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2, cyclin-dependent kinase inhibitor 1C, cyclin dependent kinase inhibitor 1C
External IDs	OMIM: 600856 HomoloGene: 133549 GeneCards: CDKN1C
Gene location (Human)
Chr.	Chromosome 11 (human)
End	2,885,775 bp
RNA expression pattern
	Top expressed in
	placenta; ; tibial nerve; ; left uterine tube; ; subcutaneous adipose tissue; ; kidney; ; canal of the cervix; ; gastric mucosa; ; fundus; ; myometrium; ; right lung;
	n/a
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; cyclin-dependent protein serine/threonine kinase inhibitor activity; protein kinase inhibitor activity; protein-containing complex binding;
Cellular component	cytoplasm; nucleus;
Biological process	positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of transcription, DNA-templated; regulation of mitotic cell cycle; negative regulation of epithelial cell proliferation; negative regulation of protein serine/threonine kinase activity; cell cycle; negative regulation of transcription, DNA-templated; negative regulation of kinase activity; negative regulation of cyclin-dependent protein kinase activity; negative regulation of phosphorylation; negative regulation of transcription by RNA polymerase II; skeletal system development; kidney development; placenta development; regulation of exit from mitosis; human ageing; myeloid cell differentiation; adrenal gland development; multicellular organism growth; neuron maturation; camera-type eye development; negative regulation of cyclin-dependent protein serine/threonine kinase activity; digestive system development; uterus development; embryonic placenta morphogenesis; genetic imprinting; regulation of lens fiber cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	1028
	n/a
	ENSG00000273707; ENSG00000129757
	n/a
	P49918
	n/a
	NM_000076; NM_001122630; NM_001122631; NM_001362474; NM_001362475
	n/a
	NP_000067; NP_001116102; NP_001116103; NP_001349403; NP_001349404
	n/a
	Wikidata
View/Edit Human

Cyclin-dependent kinase inhibitor 1C (p57, Kip2), also known as CDKN1C, is a protein which in humans is encoded by the CDKN1C imprinted gene.

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