Cushing's syndrome (veterinary)

Cushing's syndrome disease, also known as hyperadrenocorticism and spontaneous hypercortisolism, is a condition resulting from an endocrine disorder where too much adrenocorticotropic and cortisol hormones are produced, causing toxicity. It may arise in animals as well as in humans. Cushing's is an umbrella term for conditions caused by elevated cortisol and adrenocorticotropic hormone levels.

This article is about the disease in animals. For the disease in humans, see Cushing's syndrome.
Cushing's syndrome disease
Other nameshyperadrenocorticism, spontaneous hypercortisolism
Dachshund with Cushing's syndrome.
SpecialtyEndocrinology
SymptomsEnlarged stomach, lethargy, diabetes mellitus (cats)
TypesPituitary dependent, adrenal dependent, iatrogenic
Risk factorsCertain breeds, bitches
MedicationLysodren, trilostane, L-Deprenyl
Frequency0.2% to 0.28% of dogs.
Named afterHarvey Cushing

Cushing's disease most commonly refers to pituitary-dependent hyperadrenocorticism, the most common condition of Cushing's syndrome, but 'Cushing's' is used to refer to all hyperadrenocorticism conditions.

Cats are less likely to be diagnosed than dogs. Cushing's occurs infrequently in hamsters. It may be more common but due to hamsters not being routinely treated it may go undiagnosed.

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