Cubana de Aviación Flight 972

Cubana de Aviación Flight 972 was a scheduled domestic flight operated by Mexican charter airline Global Air on behalf of Cubana de Aviación, from José Martí International Airport, Havana, Cuba, to Frank País Airport in Holguín, Cuba. On 18 May 2018, the 39-year-old Boeing 737-201 Adv. operating the route crashed shortly after takeoff, near Santiago de las Vegas, 19 kilometres (12 mi; 10 nmi) from Havana city centre. Of those on board, 112 died and one passenger survived with critical injuries. There were initially four survivors, but three of them later died at a local hospital. Most of the passengers on board were Cuban nationals, although the crew was entirely Mexican.

The incident was scrutinized by Cuban safety investigators, with assistance from the United States and Mexico. While the Federal Aviation Administration has no official jurisdiction in Cuba, their assistance was voluntary and welcomed by Cuban officials due to the local investigators' general lack of experience with American-built aircraft. Additional assistance was provided by Mexico, where the aircraft was registered, and also where the airline and flight crew that owned and operated the aircraft were based. The multinational investigation ultimately determined in September 2019 that the aircraft was outside centre of gravity, and the pilots were unsuccessful in an attempt to remedy issues related to the plane's loading/weight imbalance.