Coronaridine

Coronaridine
Clinical data
ATC code	none;
Identifiers
	IUPAC name Methyl (1S,15R,17S,18S)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate;
CAS Number	467-77-6;
PubChem CID	6426909;
ChemSpider	4932328;
ChEBI	CHEBI:3887;
CompTox Dashboard (EPA)	DTXSID60963642 ;
ECHA InfoCard	100.006.727
Chemical and physical data
Formula	C21H26N2O2
Molar mass	338.451 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC;
	InChI InChI=1S/C21H26N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,13-14,19,22H,3,8-12H2,1-2H3/t13-,14+,19+,21-/m1/s1; Key:NVVDQMVGALBDGE-PZXGUROGSA-N;

Coronaridine, also known as 18-carbomethoxyibogamine, is an alkaloid found in Tabernanthe iboga and related species, including Tabernaemontana divaricata for which (under the now obsolete synonym Ervatamia coronaria) it was named.

Like ibogaine, (R)-coronaridine and (S)-coronaridine can decrease intake of cocaine and morphine in animals and it may have muscle relaxant and hypotensive activity.

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