Corey–Nicolaou macrolactonization
Corey–Nicolaou macrolactonization is a named reaction of organic chemistry, for the synthesis of lactones from hydroxy acids, found in 1974. The reaction uses 2,2'-dipyridyldisulfide and triphenylphosphine as reagents and runs in polar aprotic solvent under mild conditions.
| Corey–Nicolaou macrolactonization | |
|---|---|
| Named after | Elias James Corey K. C. Nicolaou |
| Reaction type | Name reaction |
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