Combined drug intoxication

Combined drug intoxication (CDI), or multiple drug intake (MDI), is a cause of death by drug overdose from poly drug use, often implicated in polysubstance dependence.

Deaths by combined drug intoxication are relatively rare (one in several million). In 2004, there were 3,800 deaths in the US resulting from a fatal medication error involving alcohol, while in 1983 there were fewer than 100 such deaths. It is more of a risk for older patients.