Coatomer

The coatomer is a protein complex that coats membrane-bound transport vesicles. Two types of coatomers are known:

COPI (retrograde transport from trans-Golgi network to cis-Golgi network and endoplasmic reticulum)
COPII (anterograde transport from ER to the cis-Golgi)

Coatomers are functionally analogous and evolutionarily homologous to clathrin adaptor proteins, also known as adaptins, which regulate endocytosis from the plasma membrane and transport from the trans-Golgi network to lysosomes.

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