Chuan He

Chuan He
Chuan He
	Chuan He
Born	1972; Guizhou, China
Alma mater	University of Science and Technology of China (B.S.); Massachusetts Institute of Technology (Ph.D.)
Known for	Epigenetics, DNA Methylation
Awards	Searle Scholar Award (2003); Beckman Young Investigators Award (2005); Paul Marks Prize for Cancer Research (2017); ACS Chemical Biology Lectureship (2019); Wolf Prize in Chemistry (2023)
	Scientific career
Fields	Chemical Biology, Genetics
Institutions	University of Chicago
Doctoral advisor	Stephen J. Lippard
Other academic advisors	Gregory L. Verdine

Chuan He (Chinese: 何川) is a Chinese-American chemical biologist. He currently serves as the John T. Wilson Distinguished Service Professor at the University of Chicago, and an Investigator of the Howard Hughes Medical Institute. He is best known for his work in discovering and deciphering reversible RNA methylation in post-transcriptional gene expression regulation. He was awarded the 2023 Wolf Prize in Chemistry for his work in discovering and deciphering reversible RNA methylation in post-transcriptional gene expression regulation in addition to his contributions to the invention of TAB-seq, a biochemical method that can map 5-hydroxymethylcytosine (5hmC) at base-resolution genome-wide, as well as hmC-Seal, a method that covalently labels 5hmC for its detection and profiling.

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