Estradiol valerate/hydroxyprogesterone caproate
Estradiol valerate/hydroxyprogesterone caproate (EV/OHPC), sold under the brand names Gravibinon and Injectable No. 1 (or Chinese Injectable No. 1) among others, is a combined estrogen and progestogen medication which is used in the treatment of threatened miscarriage and other indications (e.g., as a means of pseudopregnancy) and as a form of combined injectable birth control to prevent pregnancy. It contains estradiol valerate (EV), an estrogen, and hydroxyprogesterone caproate (OHPC), a progestin. The medication is given by injection into muscle once a day to once a month depending on the indication.
Estradiol valerate (top) and hydroxyprogesterone caproate (bottom) | |
| Combination of | |
|---|---|
| Estradiol valerate | Estrogen |
| Hydroxyprogesterone caproate | Progestogen |
| Clinical data | |
| Trade names | Gravibinon, Injectable No. 1, others |
| Other names | EV/OHPC; NSC-77622 |
| Routes of administration | Intramuscular injection |
| Identifiers | |
| CAS Number | |
| PubChem CID | |
| UNII | |
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