Chichibabin pyridine synthesis
Chichibabin pyridine synthesis | |
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Named after | Aleksei Chichibabin |
Reaction type | Ring forming reaction |
Identifiers | |
RSC ontology ID | RXNO:0000526 |
The Chichibabin pyridine synthesis (/ˈtʃiːtʃiːˌbeɪbiːn/) is a method for synthesizing pyridine rings. The reaction involves the condensation reaction of aldehydes, ketones, α,β-Unsaturated carbonyl compounds, or any combination of the above, with ammonia. It was reported by Aleksei Chichibabin in 1924. Methyl-substituted pyridines, which show widespread uses among multiple fields of applied chemistry, are prepared by this methodology.
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