Cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the central nervous system and meninges. The term congophilic is sometimes used because the presence of the abnormal aggregations of amyloid can be demonstrated by microscopic examination of brain tissue after staining with Congo red. The amyloid material is only found in the brain and as such the disease is not related to other forms of amyloidosis.

Cerebral amyloid angiopathy
Other namesCongophilic angiopathy
Micrograph of cerebral amyloid angiopathy using congo red stain
SpecialtyNeurology 
CausesCause of CAA is unknown
Diagnostic methodPET scan, CT scan
TreatmentManagement can be physical, occupational, or speech therapy.
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