Cellulose 1,4-β-cellobiosidase (non-reducing end)
Cellulose 1,4-β-cellobiosidase (EC 3.2.1.91, exo-cellobiohydrolase, β-1,4-glucan cellobiohydrolase, β-1,4-glucan cellobiosylhydrolase, 1,4-β-glucan cellobiosidase, exoglucanase, avicelase, CBH 1, C1 cellulase, cellobiohydrolase I, cellobiohydrolase, exo-β-1,4-glucan cellobiohydrolase, 1,4-β-D-glucan cellobiohydrolase, cellobiosidase) is an enzyme of interest for its capability of converting cellulose to useful chemicals, particularly cellulosic ethanol.
| Cellulose 1,4-β-cellobiosidase (non-reducing end) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Cellobiohydrolase monomer, Trichoderma reesei | |||||||||
| Identifiers | |||||||||
| EC no. | 3.2.1.91 | ||||||||
| CAS no. | 37329-65-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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The main technological impediment to widespread utilization of cellulose for fuels is still the lack of low-cost technologies to convert cellulose. One solution is the use of organisms that are capable of performing this conversion. Development of such organisms, such as Saccharomyces cerevisiae which is capable of secreting high levels of cellobiohydrolases, is already underway. Cellobiohydrolases are exoglucanases derived from fungi.
The systematic name is 4-β-D-glucan cellobiohydrolase (non-reducing end).