Carbonic anhydrase VI

CA6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3FE4
Identifiers
Aliases	CA6, CA-VI, GUSTIN, carbonic anhydrase 6
External IDs	OMIM: 114780 MGI: 1333786 HomoloGene: 20324 GeneCards: CA6
Gene location (Human)
Chr.	Chromosome 1 (human)
End	8,975,092 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	150,285,789 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; skin of abdomen; ; vulva; ; hair follicle; ; tongue; ; superior surface of tongue; ; thymus; ; nipple; ; blood; ; body of tongue;
	Top expressed in
	submandibular gland; ; parotid gland; ; lacrimal gland; ; lip; ; temporal muscle; ; respiratory epithelium; ; olfactory epithelium; ; masseter muscle; ; iris; ; sexually immature organism;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	carbonate dehydratase activity; zinc ion binding; metal ion binding; lyase activity; protein binding; carbonic anhydrase;
Cellular component	cytoplasm; extracellular region; cytosol; extracellular exosome; extracellular space;
Biological process	bicarbonate transport; detection of chemical stimulus involved in sensory perception of bitter taste; one-carbon metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	765
	12353
	ENSG00000131686
	ENSMUSG00000028972
	P23280; Q8N4G4
	P18761
	NM_001215; NM_001270500; NM_001270501; NM_001270502
	NM_009802
	NP_001206; NP_001257429; NP_001257430; NP_001257431
	NP_033932
	Wikidata
View/Edit Human	View/Edit Mouse

Carbonic anhydrase 6 is an enzyme that in humans is encoded by the CA6 gene. It is also called 'gustin' because of its presence in saliva, and lower-than-normal levels of salivary zinc in individuals with hypogeusia.

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