Cannabidivarin

Cannabidivarin
Clinical data
ATC code	none;
Identifiers
	IUPAC name 2-((1S,6S)-3-methyl-6-(prop-1-en-2-yl); cyclohex-2-enyl)-5-propylbenzene-1,3-diol;
CAS Number	24274-48-4 ;
PubChem CID	11601669;
DrugBank	DB14050 ;
ChemSpider	21106275 ;
UNII	I198VBV98I;
KEGG	C20217;
ChEMBL	ChEMBL2387742;
CompTox Dashboard (EPA)	DTXSID70893921 ;
ECHA InfoCard	100.236.933
Chemical and physical data
Formula	C19H26O2
Molar mass	286.415 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C=C(C)[C@H]2CCC(\C)=C/[C@@H]2c1c(O)cc(CCC)cc1O;
	InChI InChI=1S/C19H26O2/c1-5-6-14-10-17(20)19(18(21)11-14)16-9-13(4)7-8-15(16)12(2)3/h9-11,15-16,20-21H,2,5-8H2,1,3-4H3/t15-,16+/m1/s1 ; Key:REOZWEGFPHTFEI-CVEARBPZSA-N ;
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Cannabidivarin (CBDV, GWP42006) is a non-intoxicating psychoactive cannabinoid found in Cannabis. It is a homolog (chemistry) of cannabidiol (CBD), with the side-chain shortened by two methylene bridges (CH₂ units).

Although cannabidivarin (CBDV) is usually a minor constituent of the cannabinoid profile, enhanced levels of CBDV have been reported in feral populations of C. indica ( = C. sativa ssp. indica var. kafiristanica) from northwest India, and in hashish from Nepal.=

CBDV demonstrated anticonvulsant in rodent models in a single published study. It was identified for the first time in 1969 by Vollner et al.

Similarly to CBD, it has seven double bond isomers and 30 stereoisomers (see: Cannabidiol#Isomerism). It is not scheduled by Convention on Psychotropic Substances. It is being actively developed by GW Pharmaceuticals (as GWP42006) because of a demonstrated neurochemical pathway for previously observed anti-epileptic and anti-convulsive action. GW has begun several Phase-2 trials for adult epilepsy, for childhood epilepsy and for Prader-Willi Syndrome.

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