CYP1A1

CYP1A1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4I8V
Identifiers
Aliases	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX, CYPIA1, cytochrome P450 family 1 subfamily A member 1
External IDs	OMIM: 108330 MGI: 88588 HomoloGene: 68062 GeneCards: CYP1A1
Gene location (Human)
Chr.	Chromosome 15 (human)
End	74,725,536 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	57,611,107 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; islet of Langerhans; ; trachea; ; right lobe of liver; ; urinary bladder; ; mucosa of urinary bladder; ; subcutaneous adipose tissue; ; nipple; ; palpebral conjunctiva; ; saphenous vein;
	Top expressed in
	lip; ; olfactory epithelium; ; right lung; ; jejunum; ; skin of abdomen; ; duodenum; ; right lung lobe; ; temporal muscle; ; triceps brachii muscle; ; left lung;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	iron ion binding; oxygen binding; flavonoid 3'-monooxygenase activity; demethylase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; metal ion binding; steroid hydroxylase activity; catalytic activity; protein binding; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; enzyme binding; vitamin D 24-hydroxylase activity; oxidoreductase activity; aromatase activity; oxidoreductase activity, acting on diphenols and related substances as donors; monooxygenase activity; estrogen 16-alpha-hydroxylase activity; Hsp70 protein binding; Hsp90 protein binding;
Cellular component	cytoplasm; organelle membrane; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; membrane; endoplasmic reticulum; mitochondrion; mitochondrial inner membrane;
Biological process	response to immobilization stress; maternal process involved in parturition; response to hypoxia; 9-cis-retinoic acid biosynthetic process; response to organic cyclic compound; coumarin metabolic process; vitamin D metabolic process; insecticide metabolic process; response to hyperoxia; response to antibiotic; demethylation; cellular response to organic cyclic compound; response to virus; human ageing; hepatocyte differentiation; epoxygenase P450 pathway; dibenzo-p-dioxin catabolic process; response to arsenic-containing substance; response to organic substance; positive regulation of G1/S transition of mitotic cell cycle; response to vitamin A; response to lipopolysaccharide; omega-hydroxylase P450 pathway; response to wounding; dibenzo-p-dioxin metabolic process; response to nematode; response to iron(III) ion; flavonoid metabolic process; response to food; liver development; camera-type eye development; digestive tract development; cell population proliferation; response to herbicide; porphyrin-containing compound metabolic process; ethylene metabolic process; lipid hydroxylation; steroid metabolic process; cellular response to copper ion; amine metabolic process; toxin metabolic process; response to toxic substance; regulation of lipid metabolic process; heterocycle metabolic process; hydrogen peroxide biosynthetic process; developmental process; long-chain fatty acid biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	1543
	13076
	ENSG00000140465
	ENSMUSG00000032315
	P04798
	P00184
	NM_000499; NM_001319216; NM_001319217
	NM_001136059; NM_009992
	NP_000490; NP_001306145; NP_001306146
	NP_001129531; NP_034122
	Wikidata
View/Edit Human	View/Edit Mouse

Cytochrome P450, family 1, subfamily A, polypeptide 1 is a protein that in humans is encoded by the CYP1A1 gene. The protein is a member of the cytochrome P450 superfamily of enzymes.

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