CPNE6

CPNE6
Identifiers
Aliases	CPNE6, copine 6
External IDs	OMIM: 605688 MGI: 1334445 HomoloGene: 81815 GeneCards: CPNE6
Gene location (Human)
Chr.	Chromosome 14 (human)
End	24,078,100 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,754,888 bp
RNA expression pattern
	Top expressed in
	temporal lobe; ; amygdala; ; hippocampus proper; ; superior frontal gyrus; ; nucleus accumbens; ; prefrontal cortex; ; putamen; ; caudate nucleus; ; dorsolateral prefrontal cortex; ; Brodmann area 9;
	Top expressed in
	subiculum; ; dentate gyrus; ; entorhinal cortex; ; hippocampus proper; ; Region I of hippocampus proper; ; facial motor nucleus; ; superior surface of tongue; ; olfactory tubercle; ; nucleus accumbens; ; ventromedial nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; transporter activity; phosphatidylserine binding; protein binding; calcium-dependent phospholipid binding;
Cellular component	cytoplasm; endosome; perikaryon; cell projection; membrane; clathrin-coated endocytic vesicle; plasma membrane; axon; dendrite; extracellular exosome; cytoplasmic vesicle; clathrin-coated vesicle;
Biological process	cellular response to calcium ion; cell differentiation; lipid metabolism; nervous system development; glycerophospholipid biosynthetic process; positive regulation of dendrite extension; vesicle-mediated transport; chemical synaptic transmission;
	Sources:Amigo / QuickGO
Orthologs
	9362
	12891
	ENSG00000100884
	ENSMUSG00000022212
	O95741
	Q9Z140
	NM_001280558; NM_006032
	NM_001136057; NM_001146183; NM_009947; NM_001360193
	NP_001267487; NP_006023
	NP_001129529; NP_001139655; NP_034077; NP_001347122
	Wikidata
View/Edit Human	View/Edit Mouse

Copine-6 is a protein that in humans is encoded by the CPNE6 gene.

This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.

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