Carboxypeptidase A1

CPA1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2V77, 3FJU, 4UEZ, 4UF4, 4UEE, 4UEF
Identifiers
Aliases	CPA1, CPA, carboxypeptidase A1
External IDs	OMIM: 114850 MGI: 88478 HomoloGene: 55609 GeneCards: CPA1
Gene location (Human)
Chr.	Chromosome 7 (human)
End	130,388,114 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	30,645,362 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; islet of Langerhans; ; right coronary artery; ; right lobe of liver; ; left uterine tube; ; canal of the cervix; ; right uterine tube; ; right adrenal gland; ; oocyte; ; body of stomach;
	Top expressed in
	pyloric antrum; ; islet of Langerhans; ; secondary oocyte; ; duodenum; ; sexually immature organism; ; left lobe of liver; ; left lung lobe; ; morula; ; atrioventricular valve; ; endocardial cushion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	carboxypeptidase activity; zinc ion binding; peptidase activity; exopeptidase activity; hydrolase activity; metallopeptidase activity; metal ion binding; metallocarboxypeptidase activity; protein binding;
Cellular component	extracellular region; extracellular space;
Biological process	proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	1357
	109697
	ENSG00000091704
	ENSMUSG00000054446
	P15085
	Q7TPZ8
	NM_001868
	NM_025350
	NP_001859
	NP_079626
	Wikidata
View/Edit Human	View/Edit Mouse

Carboxypeptidase A1 is an enzyme that in humans is encoded by the CPA1 gene.

Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A1 and A2 forms are monomeric proteins with different biochemical properties. Carboxypeptidase A1 is a monomeric pancreatic exopeptidase. It is involved in zymogen inhibition.

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