COVID-19 pandemic in Arizona

The COVID-19 pandemic was confirmed to have reached the U.S. state of Arizona in January 2020. As of June 3, 2021 Arizona public health authorities reported 322 new cases of COVID-19 and five deaths, bringing the cumulative totals since the start of the pandemic to 882,691 cases and 17,653 deaths. 12.3% of the state's population has been positively diagnosed with COVID-19 since the first case was reported on January 26, 2020.

In the two-month period after Governor of Arizona Doug Ducey abruptly ended Arizona's statewide lockdown on May 15, 2020, the seven-day moving average of new COVID-19 cases in Arizona soared, from an average of 377 cases per day to 3,249 cases on July 15. On July 8, Arizona reported as many new cases of COVID-19 as the entire European Union, while having 1/60th of the population. On June 17, Governor Ducey, under pressure due to rising COVID cases, publicly encouraged Arizona citizens to wear masks and allowed individual cities and counties to issue mask mandates. No statewide mandate was issued, but most major cities and counties in AZ issued local mandates. COVID-19 cases and deaths continued to rise through July, with 172 deaths reported on July 30, 2020.

After four months during which the day over day increase in new COVID-19 cases never dropped below 1%, in August the case rate dropped dramatically, to less than 900 new cases per day. A generally low new case rate continued in Arizona through October 2020 but in November a second major COVID-19 surge began, reaching new records in early January 2021. January 3's 17,236 new cases and January 12's 335 deaths both set new single day records in Arizona. The COVID-19 pandemic in the Navajo Nation has been particularly serious because of poor health, food and limited access to essential services.

As of March 10, 2023, Arizona has administered 14,526,275 COVID-19 vaccine doses. Arizona has fully vaccinated 4,809,730 people, equivalent to 65% percent of the population.