Calponin 2

CNN2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WYN
Identifiers
Aliases	CNN2, calponin 2
External IDs	OMIM: 602373 MGI: 105093 HomoloGene: 3215 GeneCards: CNN2
Gene location (Human)
Chr.	Chromosome 19 (human)
End	1,039,068 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	79,831,896 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; right lung; ; left uterine tube; ; blood; ; upper lobe of left lung; ; right coronary artery; ; thoracic aorta; ; ascending aorta; ; gallbladder; ; popliteal artery;
	Top expressed in
	external carotid artery; ; internal carotid artery; ; left lung lobe; ; calvaria; ; blood; ; right lung; ; right lung lobe; ; belly cord; ; molar; ; atrium;
	More reference expression data
	n/a
Gene ontology
Molecular function	actin binding; calmodulin binding; cadherin binding;
Cellular component	extracellular exosome; cytoskeleton; membrane; focal adhesion; stress fiber; cell-cell junction; extracellular region; specific granule lumen; tertiary granule lumen;
Biological process	actomyosin structure organization; cellular response to mechanical stimulus; cytoskeleton organization; regulation of actin filament-based process; neutrophil degranulation; interleukin-12-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	1265
	12798
	ENSG00000064666
	ENSMUSG00000004665
	Q99439
	Q08093
	NM_201277; NM_001303499; NM_001303501; NM_004368
	NM_007725
	NP_001290428; NP_001290430; NP_004359; NP_958434
	NP_031751
	Wikidata
View/Edit Human	View/Edit Mouse

Calponin 2 is a protein that in humans is encoded by the CNN2 gene.

The CNN2 gene is located at 19p13.3 in the human chromosomal genome, encoding the protein calponin 2. Calponin 2 is one of the three isoforms of calponin and an actin filament-associated regulatory protein with wide tissue distributions. Human calponin 2 is a 33.7-kDa protein consisting of 309 amino acids with an isoelectric point (pI) of 7.23. Accordingly, it is also known as neutral calponin.

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