CHRNB4

CHRNB4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ASG
Identifiers
Aliases	CHRNB4, cholinergic receptor nicotinic beta 4 subunit
External IDs	OMIM: 118509 MGI: 87892 HomoloGene: 20196 GeneCards: CHRNB4
Gene location (Human)
Chr.	Chromosome 15 (human)
End	78,727,754 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	54,956,063 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; sural nerve; ; right adrenal gland; ; appendix; ; thymus; ; lymph node; ; rectum; ; smooth muscle tissue; ; islet of Langerhans; ; transverse colon;
	Top expressed in
	habenula; ; pineal gland; ; ciliary body; ; pretectal area; ; iris; ; Paneth cell; ; adrenal gland; ; carotid body; ; lens; ; ileum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	acetylcholine binding; acetylcholine receptor activity; ion channel activity; ligand-gated ion channel activity; protein heterodimerization activity; extracellular ligand-gated ion channel activity; protein binding; acetylcholine-gated cation-selective channel activity; transmembrane signaling receptor activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	acetylcholine-gated channel complex; integral component of membrane; postsynaptic membrane; membrane; plasma membrane; synapse; integral component of plasma membrane; cell junction; neuron projection; specific granule membrane; tertiary granule membrane; cholinergic synapse;
Biological process	smooth muscle contraction; locomotory behavior; regulation of smooth muscle contraction; protein heterooligomerization; positive regulation of transmission of nerve impulse; regulation of membrane potential; response to nicotine; synaptic transmission, cholinergic; ion transport; regulation of neurotransmitter secretion; behavioral response to nicotine; synaptic transmission involved in micturition; action potential; signal transduction; neutrophil degranulation; regulation of postsynaptic membrane potential; excitatory postsynaptic potential; ion transmembrane transport; chemical synaptic transmission; neuromuscular synaptic transmission; nervous system process;
	Sources:Amigo / QuickGO
Orthologs
	1143
	108015
	ENSG00000117971
	ENSMUSG00000035200
	P30926
	Q8R493
	NM_000750; NM_001256567
	NM_148944
	NP_000741; NP_001243496
	NP_683746
	Wikidata
View/Edit Human	View/Edit Mouse

Neuronal acetylcholine receptor subunit beta-4 is a protein that in humans is encoded by the CHRNB4 gene.

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