CEP152

CEP152
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4N7V
Identifiers
Aliases	CEP152, MCPH4, MCPH9, SCKL5, centrosomal protein 152
External IDs	OMIM: 613529 MGI: 2139083 HomoloGene: 37159 GeneCards: CEP152
Gene location (Human)
Chr.	Chromosome 15 (human)
End	48,811,146 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	125,467,033 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; sperm; ; sural nerve; ; Achilles tendon; ; bone marrow; ; spongy bone; ; bone marrow cells; ; monocyte; ; ganglionic eminence; ; placenta;
	Top expressed in
	saccule; ; Paneth cell; ; medullary collecting duct; ; otic placode; ; secondary oocyte; ; Jacobson's organ; ; renal corpuscle; ; pharynx; ; primitive streak; ; bone marrow;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein kinase binding; protein binding;
Cellular component	deuterosome; cytosol; centriole; nucleoplasm; cytoplasm; pericentriolar material; microtubule organizing center; cytoskeleton; centrosome;
Biological process	cell projection organization; G2/M transition of mitotic cell cycle; de novo centriole assembly involved in multi-ciliated epithelial cell differentiation; centrosome duplication; centriole replication; ciliary basal body-plasma membrane docking; regulation of G2/M transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	22995
	99100
	ENSG00000103995
	ENSMUSG00000068394
	O94986
	A2AUM9
	NM_001194998; NM_014985
	NM_001081091
	NP_001181927; NP_055800
	NP_001074560
	Wikidata
View/Edit Human	View/Edit Mouse

Centrosomal protein of 152 kDa, also known as Cep152, is a protein that in humans is encoded by the CEP152 gene. It is the ortholog of the Drosophila melanogaster gene asterless (asl) and both are required for centriole duplication.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.