CDX4 (gene)

CDX4
Identifiers
Aliases	CDX4, caudal type homeobox 4
External IDs	OMIM: 300025 MGI: 88362 HomoloGene: 3806 GeneCards: CDX4
Gene location (Human)
Chr.	X chromosome (human)
End	73,455,171 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	102,374,198 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; embryo; ; skin of limb; ; nervous system; ; reproductive system; ; reproductive organ; ; gonad; ; tibial nerve;
	Top expressed in
	urethra; ; male urethra; ; primitive streak; ; allantois; ; proximal tubule; ; blastocyst; ; islet of Langerhans; ; exocrine gland; ; liver; ; ureter;
	More reference expression data
	n/a
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity;
Cellular component	nucleus;
Biological process	animal organ morphogenesis; multicellular organism development; labyrinthine layer development; cell differentiation; blood vessel development; anterior/posterior axis specification; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; anterior/posterior pattern specification; placenta development; transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	1046
	12592
	ENSG00000131264
	ENSMUSG00000031326
	O14627
	Q07424
	NM_005193
	NM_007674
	NP_005184
	NP_031700
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein CDX-4 is a protein that in humans is encoded by the CDX4 gene. This gene is a member of the caudal-related homeobox transcription factor family that also includes CDX1 and CDX2.

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