Cyclin E1

CCNE1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1W98
Identifiers
Aliases	CCNE1, CCNE, pcyclin E1
External IDs	OMIM: 123837 MGI: 88316 HomoloGene: 14452 GeneCards: CCNE1
Gene location (Human)
Chr.	Chromosome 19 (human)
End	29,824,312 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	37,806,959 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; placenta; ; bone marrow; ; amniotic fluid; ; spongy bone; ; stromal cell of endometrium; ; bone marrow cells; ; cerebellar hemisphere; ; rectum; ; embryo;
	Top expressed in
	morula; ; condyle; ; fossa; ; internal carotid artery; ; primitive streak; ; somite; ; yolk sac; ; maxillary prominence; ; external carotid artery; ; Paneth cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity; kinase activity; cyclin-dependent protein serine/threonine kinase regulator activity; protein binding; androgen receptor binding; protein kinase binding; cyclin-dependent protein serine/threonine kinase activity; protein kinase activity;
Cellular component	cytosol; cyclin-dependent protein kinase holoenzyme complex; nucleoplasm; nucleus; cyclin E1-CDK2 complex; cytoplasm; centrosome;
Biological process	androgen receptor signaling pathway; Wnt signaling pathway; regulation of transcription involved in G1/S transition of mitotic cell cycle; regulation of cell cycle; cell division; positive regulation of transcription, DNA-templated; protein phosphorylation; DNA replication initiation; cell cycle; regulation of protein kinase activity; negative regulation of transcription by RNA polymerase II; telomere maintenance; homologous chromosome pairing at meiosis; chromosome organization involved in meiotic cell cycle; G1/S transition of mitotic cell cycle; regulation of cyclin-dependent protein serine/threonine kinase activity; mitotic cell cycle; regulation of mitotic nuclear division; positive regulation of cell population proliferation; positive regulation of cell cycle; positive regulation of G1/S transition of mitotic cell cycle; mitotic cell cycle phase transition;
	Sources:Amigo / QuickGO
Orthologs
	898
	12447
	ENSG00000105173
	ENSMUSG00000002068
	P24864
	Q61457
	NM_001238; NM_057182; NM_001322259; NM_001322261; NM_001322262
	NM_007633
NP_001229; NP_001309188; NP_001309190; NP_001309191; NP_001309188.1;
	NP_001309190.1
	NP_031659
	Wikidata
View/Edit Human	View/Edit Mouse

G1/S-specific cyclin-E1 is a protein that in humans is encoded by the CCNE1 gene.

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