Cyclin D1

CCND1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2W96, 2W99, 2W9F, 2W9Z
Identifiers
Aliases	CCND1, BCL1, D11S287E, PRAD1, U21B31, cyclin D1
External IDs	OMIM: 168461 MGI: 88313 HomoloGene: 1334 GeneCards: CCND1
Gene location (Human)
Chr.	Chromosome 11 (human)
End	69,654,474 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	144,493,662 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; sural nerve; ; nipple; ; tibia; ; hair follicle; ; skin of abdomen; ; palpebral conjunctiva; ; right coronary artery; ; oral cavity; ; human penis;
	Top expressed in
	calvaria; ; superior cervical ganglion; ; seminal vesicula; ; corneal stroma; ; saccule; ; vas deferens; ; dermis; ; lacrimal gland; ; renal corpuscle; ; crypt of lieberkuhn of small intestine;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein kinase activity; transcription corepressor activity; transcription factor binding; histone deacetylase binding; kinase activity; cyclin-dependent protein serine/threonine kinase regulator activity; protein binding; enzyme binding; proline-rich region binding; protein kinase binding; cyclin-dependent protein serine/threonine kinase activity; protein-containing complex binding;
Cellular component	cytoplasm; cytosol; cyclin-dependent protein kinase holoenzyme complex; membrane; bicellular tight junction; transcription repressor complex; intracellular anatomical structure; nucleoplasm; nucleus;
Biological process	cellular response to organic substance; mammary gland epithelial cell proliferation; positive regulation of mammary gland epithelial cell proliferation; response to estradiol; positive regulation of protein phosphorylation; Leydig cell differentiation; regulation of transcription, DNA-templated; response to organic cyclic compound; response to steroid hormone; response to corticosterone; negative regulation of Wnt signaling pathway; response to magnesium ion; response to glucocorticoid; re-entry into mitotic cell cycle; negative regulation of transcription by RNA polymerase II; Wnt signaling pathway; mammary gland alveolus development; response to organic substance; transcription, DNA-templated; response to vitamin E; regulation of cell cycle; response to iron ion; response to estrogen; response to calcium ion; cell division; cellular response to DNA damage stimulus; endoplasmic reticulum unfolded protein response; protein phosphorylation; regulation of G1/S transition of mitotic cell cycle; liver regeneration; mitotic G1 DNA damage checkpoint signaling; animal organ regeneration; response to organonitrogen compound; positive regulation of cell population proliferation; positive regulation of cyclin-dependent protein serine/threonine kinase activity; canonical Wnt signaling pathway; response to UV-A; cell cycle; liver development; positive regulation of G2/M transition of mitotic cell cycle; lactation; response to ethanol; response to leptin; negative regulation of epithelial cell differentiation; fat cell differentiation; response to X-ray; positive regulation of cell cycle; transcription initiation from RNA polymerase II promoter; G1/S transition of mitotic cell cycle; cytokine-mediated signaling pathway; positive regulation of epithelial cell proliferation; regulation of cyclin-dependent protein serine/threonine kinase activity; mitotic cell cycle; regulation of mitotic nuclear division; positive regulation of G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	595
	12443
	ENSG00000110092
	ENSMUSG00000070348
	P24385
	P25322
	NM_053056
	NM_007631; NM_001379248
	NP_444284
	NP_031657; NP_001366177
	Wikidata
View/Edit Human	View/Edit Mouse

Cyclin D1 is a protein that in humans is encoded by the CCND1 gene.

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