CAND1

CAND1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1U6G, 4A0C
Identifiers
Aliases	CAND1, TIP120, TIP120A, cullin associated and neddylation dissociated 1
External IDs	OMIM: 607727 MGI: 1261820 HomoloGene: 10202 GeneCards: CAND1
Gene location (Human)
Chr.	Chromosome 12 (human)
End	67,319,953 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	119,075,960 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; stromal cell of endometrium; ; Achilles tendon; ; islet of Langerhans; ; endothelial cell; ; appendix; ; parietal pleura; ; germinal epithelium; ; thymus; ; body of pancreas;
	Top expressed in
	spermatocyte; ; spermatid; ; somite; ; maxillary prominence; ; cumulus cell; ; morula; ; primitive streak; ; abdominal wall; ; seminiferous tubule; ; supraoptic nucleus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	TBP-class protein binding; protein binding;
Cellular component	cytoplasm; cullin-RING ubiquitin ligase complex; Golgi apparatus; extracellular exosome; membrane; nucleus; ubiquitin ligase complex; extracellular region; secretory granule lumen; ficolin-1-rich granule lumen; nucleoplasm; cytosol;
Biological process	positive regulation of transcription, DNA-templated; SCF complex assembly; cell differentiation; positive regulation of RNA polymerase II transcription preinitiation complex assembly; negative regulation of catalytic activity; protein ubiquitination; neutrophil degranulation; cellular iron ion homeostasis; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	55832
	71902
	ENSG00000111530
	ENSMUSG00000020114
	Q86VP6
	Q6ZQ38
	NM_001329674; NM_001329675; NM_001329676; NM_018448
	NM_027994
	NP_001316603; NP_001316604; NP_001316605; NP_060918
	NP_082270
	Wikidata
View/Edit Human	View/Edit Mouse

Cullin-associated NEDD8-dissociated protein 1 is a protein that in humans is encoded by the CAND1 gene.

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