Bromal hydrate

Bromal hydrate is an organobromine compound with the chemical formula C2H3Br3O2. It is the bromine analogue of chloral hydrate. Bromal hydrate forms when bromal is reacted with water. It decomposes to bromal and water upon distillation. It has hypnotic and analgesic properties but acts like a stimulant at lower doses. Bromal hydrate is more physiologically active than its chlorine analogue, chloral hydrate. Its direct effect on the heart muscles is stronger than that of chloral hydrate. Its analgesic effects were attributed to the proposed metabolism to bromoform.

Bromal hydrate
Names
IUPAC name
2,2,2-Tribromo-1,1-ethanediol
Other names
tribromoethylidene glycol
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.007.340
EC Number
  • 208-073-2
PubChem CID
UNII
  • InChI=1S/C2H3Br3O2/c3-2(4,5)1(6)7/h1,6-7H
    Key: NJHVMXFNIZTTBV-UHFFFAOYSA-N
SMILES
  • C(C(Br)(Br)Br)(O)O
Properties
C2H3Br3O2
Molar mass 298.756 g·mol−1
Appearance white crystalline solid with bromal-like smell and taste
Melting point 53.5 °C (128.3 °F; 326.6 K)
Soluble
Solubility Soluble in ethanol, Diethyl ether, chloroform and Glycerin
Hazards
GHS labelling:
Warning
H302, H315, H319, H335
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

It was also tried as a medication for epilepsy, but was found ineffective.

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