Bovine serum albumin

Bovine serum albumin (BSA or "Fraction V") is a serum albumin protein derived from cows. It is often used as a protein concentration standard in lab experiments.

This article is about albumin specific to cows. For the human variant, see human serum albumin. For the family of mammalian albumins, see serum albumin.
albumin
Identifiers
OrganismBos taurus (domestic cow)
SymbolALB
Entrez280717
HomoloGene105925
RefSeq (mRNA)NM_180992
RefSeq (Prot)NP_851335
UniProtP02769
Other data
Chromosome6: 91.54 - 91.57 Mb
Search for
StructuresSwiss-model
DomainsInterPro

The nickname "Fraction V" refers to albumin being the fifth fraction of the original Edwin Cohn purification methodology that made use of differential solubility characteristics of plasma proteins. By manipulating solvent concentrations, pH, salt levels, and temperature, Cohn was able to pull out successive "fractions" of blood plasma. The process was first commercialized with human albumin for medical use and later adopted for production of BSA.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.