Bizarre parosteal osteochondromatous proliferation
Bizarre parosteal osteochondromatous proliferation (BPOP), also known as Nora's lesion, is a type of non-cancerous bone tumor belonging to the group of cartilage tumors. It is generally seen in the tubular bones of the hands and feet, where it presents with a rapidly enlarging painless lump in a finger or toe.
| Bizarre parosteal osteochondromatous proliferation | |
|---|---|
| Other names | Nora lesion or Nora disease |
| Specialty | Orthopedics |
| Symptoms | Painless lump in finger or toe |
| Risk factors | Possibly trauma in a minority |
| Diagnostic method | Medical imaging |
| Differential diagnosis | Mainly subungal exostosis |
| Treatment | Surgical excision. |
| Prognosis | Up to 50% recur after surgery |
| Frequency | Rare, <5% of cartilage tumors, M=F |
It is composed of bone, cartilage and spindle cells. Some people report previous trauma.
Diagnosis is by medical imaging. Treatment is by surgical excision. Up to 50% recur after surgery.
It is rare, and occurs more often in the 20s and 30s. Combined with subungal exostosis, it accounts for less than 5% of cartilage tumors. Males and females are affected equally. The condition was first described by Frederick E. Nora in 1983.
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