Bicine

Bicine is an organic compound used as a buffering agent. It is one of Good's buffers and has a pKa of 8.35 at 20 °C. It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone.

Bicine
Names
IUPAC name
N,N-Bis(2-hydroxyethyl)glycine
Systematic IUPAC name
[Bis(2-hydroxyethyl)amino]acetic acid
Other names
Diethylolglycine; Diethanol glycine; Dihydroxyethylglycine; BHG
Identifiers
3D model (JSmol)
Abbreviations DHEG
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.005.233
PubChem CID
UNII
  • InChI=1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11) Y
    Key: FSVCELGFZIQNCK-UHFFFAOYSA-N Y
  • InChI=1/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)
    Key: FSVCELGFZIQNCK-UHFFFAOYAV
SMILES
  • O=C(O)CN(CCO)CCO
Properties
C6H13NO4
Molar mass 163.17 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Bicine is a contaminant in amine systems used for gas sweetening. It is formed by amine degradation in the presence of O2, SO2, H2S or Thiosulfate.

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