Benzylpiperazine

Benzylpiperazine
Clinical data
Routes of; administration	Oral, intravenous, insufflation
ATC code	none;
Legal status
Legal status	AU: S9 (Prohibited substance); BR: Class F2 (Prohibited psychotropics); CA: Schedule III; DE: Anlage II (Authorized trade only, not prescriptible); NZ: Class C; UK: POM (Prescription only); US: Schedule I;
Pharmacokinetic data
Bioavailability	Unknown
Metabolism	Hepatic
Elimination half-life	5.5 Hours
Excretion	Renal
Identifiers
	IUPAC name 1-Benzylpiperazine;
CAS Number	2759-28-6 ;
PubChem CID	75994;
ChemSpider	68493 ;
UNII	3UG152ZU0E;
KEGG	C22780;
ChEBI	CHEBI:83537 ;
ChEMBL	ChEMBL113600 ;
CompTox Dashboard (EPA)	DTXSID0022197 ;
ECHA InfoCard	100.018.567
Chemical and physical data
Formula	C11H16N2
Molar mass	176.263 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1(CN2CCNCC2)=CC=CC=C1;
	InChI InChI=1S/C11H16N2/c1-2-4-11(5-3-1)10-13-8-6-12-7-9-13/h1-5,12H,6-10H2 ; Key:IQXXEPZFOOTTBA-UHFFFAOYSA-N ;
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Benzylpiperazine (BZP) is a substance often used as a recreational drug and is known to have euphoriant and stimulant properties. Several studies conducted between 2000 and 2011 found that the effects of BZP are similar to amphetamine, although BZP's dosage is roughly 10 times higher by weight.

Adverse effects have been reported following its use including acute psychosis, renal toxicity and seizures. Deaths from piperazine derivatives are extremely rare, but there has been at least one death apparently due to BZP alone. Its sale is banned in several countries, including Australia, Canada, New Zealand, the United States, the Republic of Ireland, the United Kingdom, Bulgaria, Romania and other parts of Europe.

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