Benzocaine

Benzocaine
Clinical data
Trade names	Anbesol, Lanacane, Orajel, others
AHFS/Drugs.com	Monograph
Routes of; administration	Topical, Oral
ATC code	C05AD03 (WHO) D04AB04 (WHO), QN01AX92 (WHO), N01BA05 (WHO), R02AD01 (WHO);
Legal status
Legal status	UK: GSL, P; US: OTC;
Identifiers
	IUPAC name Ethyl 4-aminobenzoate;
CAS Number	94-09-7 ;
PubChem CID	2337;
DrugBank	DB01086 ;
ChemSpider	13854242 ;
UNII	U3RSY48JW5;
KEGG	D00552 ;
ChEBI	CHEBI:116735 ;
ChEMBL	ChEMBL278172 ;
CompTox Dashboard (EPA)	DTXSID8021804 ;
ECHA InfoCard	100.002.094
Chemical and physical data
Formula	C9H11NO2
Molar mass	165.192 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(OCC)c1ccc(N)cc1;
	InChI InChI=1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3 ; Key:BLFLLBZGZJTVJG-UHFFFAOYSA-N ;
	(verify)

Benzocaine, sold under the brand name Orajel amongst others, is a local anesthetic, belonging to the amino ester drug class, commonly used as a topical painkiller or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments such as products for oral ulcers. It is combined with antipyrine to form A/B ear drops. In the US, products containing benzocaine for oral application are contraindicated in children younger than two years old. In the European Union, the contraindication applies to children under 12 years of age.

It was first synthesised in 1890 in Germany and approved for medical use in 1902.

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