Benserazide

Benserazide is a peripherally acting aromatic L-amino acid decarboxylase or DOPA decarboxylase inhibitor, which is unable to cross the blood–brain barrier.

Benserazide
Clinical data
Other namesSerazide, RO 4-4602
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • AU: B3
ATC code
  • None
Identifiers
  • (RS)-2-Amino-3-hydroxy-N′-(2,3,4-trihydroxybenzyl)propanehydrazide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC10H15N3O5
Molar mass257.246 g·mol−1
3D model (JSmol)
SMILES
  • NC(CO)C(=O)NNCC1=C(O)C(O)=C(O)C=C1
  • InChI=1S/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18) Y
  • Key:BNQDCRGUHNALGH-UHFFFAOYSA-N Y

  • as HCl: InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H
  • Key:ULFCBIUXQQYDEI-UHFFFAOYSA-N
  (verify)

It is on the World Health Organization's List of Essential Medicines.

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