Barton–McCombie deoxygenation

The Barton–McCombie deoxygenation is an organic reaction in which a hydroxy functional group in an organic compound is replaced by a hydrogen to give an alkyl group. It is named after British chemists Sir Derek Harold Richard Barton and Stuart W. McCombie.

Barton–McCombie deoxygenation
Named after Derek Harold Richard Barton
Stuart W. McCombie
Reaction type Organic redox reaction
Identifiers
Organic Chemistry Portal barton-mccombie-reaction
RSC ontology ID RXNO:0000134

This deoxygenation reaction is a radical substitution. In the related Barton decarboxylation the reactant is a carboxylic acid.

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