Auxilin

DNAJC6
Identifiers
Aliases	DNAJC6, DJC6, PARK19, Auxilin, DnaJ heat shock protein family (Hsp40) member C6
External IDs	OMIM: 608375 MGI: 1919935 HomoloGene: 8865 GeneCards: DNAJC6
Gene location (Human)
Chr.	Chromosome 1 (human)
End	65,415,871 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	101,499,996 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; orbitofrontal cortex; ; middle temporal gyrus; ; pons; ; inferior olivary nucleus; ; Brodmann area 46; ; superior vestibular nucleus; ; Region I of hippocampus proper; ; postcentral gyrus;
	Top expressed in
	medial dorsal nucleus; ; dorsomedial hypothalamic nucleus; ; ventral tegmental area; ; pontine nuclei; ; medial geniculate nucleus; ; paraventricular nucleus of hypothalamus; ; lateral geniculate nucleus; ; piriform cortex; ; primary motor cortex; ; subiculum;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein tyrosine phosphatase activity; SH3 domain binding; phosphoprotein phosphatase activity; hydrolase activity; clathrin binding;
Cellular component	cytosol; synapse; vesicle; postsynaptic density; cytoplasm; intracellular membrane-bounded organelle; presynapse;
Biological process	peptidyl-tyrosine dephosphorylation; regulation of clathrin-dependent endocytosis; protein dephosphorylation; clathrin coat disassembly; receptor-mediated endocytosis; membrane organization; synaptic vesicle uncoating; clathrin-dependent endocytosis;
	Sources:Amigo / QuickGO
Orthologs
	9829
	72685
	ENSG00000116675
	ENSMUSG00000028528
	O75061
	Q80TZ3
	NM_001256864; NM_001256865; NM_014787
NM_001164583; NM_001164584; NM_001164585; NM_198412; NM_001355179;
	NM_001355180
	NP_001243793; NP_001243794; NP_055602
NP_001158055; NP_001158056; NP_001158057; NP_940804; NP_001342108;
	NP_001342109
	Wikidata
View/Edit Human	View/Edit Mouse

Putative tyrosine-protein phosphatase auxilin is an enzyme that in humans is encoded by the DNAJC6 gene.

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