Artemether/lumefantrine

Artemether/lumefantrine
Combination of
Artemether	Antimalarial
Lumefantrine	Antimalarial
Clinical data
Trade names	Coartem, Riamet, Falcynate-LF
AHFS/Drugs.com	Monograph
MedlinePlus	a609024
Pregnancy; category	AU: D;
Routes of; administration	By mouth
ATC code	P01BF01 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); US: ℞-only;
Identifiers
CAS Number	141204-94-6;
ChemSpider	21106282 ;
	(what is this?) (verify)

Artemether/lumefantrine, sold under the trade name Coartem among others, is a combination of the two medications artemether and lumefantrine. It is used to treat malaria caused by Plasmodium falciparum that is not treatable with chloroquine. It is not typically used to prevent malaria. It is taken by mouth.

Common side effects include muscle and joint pains, fever, loss of appetite, and headache. Serious side effects include prolongation of the QT interval. While not well studied, it appears to be safe for use in pregnancy. The dose does not need changing in those with mild or moderate kidney or liver problems.

This combination came into medical use in 1992. and was developed in China. It is on the World Health Organization's List of Essential Medicines. It is not available as a generic medication.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.