Aristolochic acid

Aristolochic acid I
Names
	Preferred IUPAC name 8-Methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid
	Other names Aristinic acid; Aristolochia yellow; Aristolochic acid A; Aristolochin;Aristolochine; Descresept; Tardolyt;TR 1736
Identifiers
CAS Number	313-67-7 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL93353 ;
ChemSpider	2149 ;
KEGG	C08469 ;
PubChem CID	2236;
UNII	94218WFP5T ;
	InChI InChI=1S/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20) Key: BBFQZRXNYIEMAW-UHFFFAOYSA-N ; InChI=1/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20) Key: BBFQZRXNYIEMAW-UHFFFAOYAG;
	SMILES [O-][N+](=O)c1cc4c(c2c1c(C(=O)O)cc3OCOc23)cccc4OC;
Properties
Chemical formula	C17H11NO7
Molar mass	341.275 g·mol−1
Appearance	yellow powder
Melting point	260 to 265 °C (500 to 509 °F; 533 to 538 K)
Solubility in water	Slightly soluble
Hazards
NFPA 704 (fire diamond)	2 1 0
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Aristolochic acids (English: /əˌrɪstəˈloʊkɪk/) are a family of carcinogenic, mutagenic, and nephrotoxic phytochemicals commonly found in the flowering plant family Aristolochiaceae (birthworts). Aristolochic acid (AA) I is the most abundant one. The family Aristolochiaceae includes the genera Aristolochia and Asarum (wild ginger), which are commonly used in Chinese herbal medicine. Although these compounds are widely associated with kidney problems, liver and urothelial cancers, the use of AA-containing plants for medicinal purposes has a long history. The FDA has issued warnings regarding consumption of AA-containing supplements.

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