Acecarbromal

Acecarbromal (INN) (brand names Sedamyl, Abasin, Carbased, Paxarel, Sedacetyl, numerous others), also known as acetylcarbromal and acetyladalin, is a hypnotic and sedative drug of the ureide (acylurea) group discovered by Bayer in 1917 that was formerly marketed in the United States and Europe. It is also used in combination with extract of quebracho and vitamin E as a treatment for erectile dysfunction under the brand name Afrodor in Europe. Acecarbromal is structurally related to the barbiturates, which are basically cyclized ureas. Prolonged use is not recommended as it can cause bromine poisoning.

Acecarbromal
Names
Preferred IUPAC name
N-(Acetylcarbamoyl)-2-bromo-2-ethylbutanamide
Other names
1-Acetyl-3-(2-bromo-2-ethylbutyryl)urea
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.000.953
EC Number
  • 201-047-1
KEGG
MeSH acecarbromal
PubChem CID
UNII
  • InChI=1S/C9H15BrN2O3/c1-4-9(10,5-2)7(14)12-8(15)11-6(3)13/h4-5H2,1-3H3,(H2,11,12,13,14,15) Y
    Key: SAZUGELZHZOXHB-UHFFFAOYSA-N Y
SMILES
  • CCC(Br)(CC)C(=O)NC(=O)NC(C)=O
Properties
C9H15BrN2O3
Molar mass 279.134 g·mol−1
Pharmacology
Routes of
administration
Oral
Legal status
  • In general: ℞ (Prescription only)
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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