Abrin

Abrin
Identifiers
CAS Number	1393-62-0 ;
ChemSpider	none;
KEGG	C20068;
RTECS number	AA5250000;
UNII	6YCF89P8OX ;
UN number	3462
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

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Structures	Swiss-model
Domains	InterPro

Abrin-a
Abrin-a
	Abrin-a structure (PDB: 1ABR). The A chain is shown in blue and the B chain in olive. A single peptide is cleaved into the two chains.
Identifiers
Organism	Abrus precatorius
Symbol	?
CAS number	1393-62-0
UniProt	P11140
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Abrin is an extremely toxic toxalbumin found in the seeds of the rosary pea (or jequirity pea), Abrus precatorius. It has a median lethal dose of 0.7 micrograms per kilogram of body mass when given to mice intravenously (approximately 31.4 times more toxic than ricin, being 22 micrograms per kilogram). The median toxic dose for humans ranges from 10 to 1000 micrograms per kilogram when ingested and is 3.3 micrograms per kilogram when inhaled.

Abrin is a ribosome inhibiting protein like ricin, a toxin which can be found in the seeds of the castor oil plant, and pulchellin, a toxin which can be found in the seeds of Abrus pulchellus. Abrin is classed as a "select agent" under U.S. law.

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