ATP1A3

ATP1A3
Identifiers
Aliases	ATP1A3, AHC2, DYT12, RDP, CAPOS, ATPase Na+/K+ transporting subunit alpha 3, ATP1A1, DEE99
External IDs	OMIM: 182350 MGI: 88107 HomoloGene: 113729 GeneCards: ATP1A3
Gene location (Human)
Chr.	Chromosome 19 (human)
End	41,997,497 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	24,705,383 bp
RNA expression pattern
	Top expressed in
	superior frontal gyrus; ; prefrontal cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; hypothalamus; ; hippocampus proper; ; temporal lobe; ; amygdala; ; nucleus accumbens; ; left ventricle;
	Top expressed in
	superior frontal gyrus; ; subiculum; ; dorsomedial hypothalamic nucleus; ; pontine nuclei; ; cerebellar cortex; ; dorsal tegmental nucleus; ; habenula; ; superior colliculus; ; lateral geniculate nucleus; ; inferior colliculus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	steroid hormone binding; nucleotide binding; chaperone binding; P-type sodium:potassium-exchanging transporter activity; metal ion binding; P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential; heparan sulfate proteoglycan binding; D1 dopamine receptor binding; hydrolase activity; ATP binding; amyloid-beta binding; P-type potassium transmembrane transporter activity; ion antiporter activity involved in regulation of presynaptic membrane potential;
Cellular component	cytoplasm; integral component of membrane; dendritic spine neck; extracellular vesicle; Golgi apparatus; membrane; myelin sheath; plasma membrane; synapse; sodium:potassium-exchanging ATPase complex; axon; dendritic spine head; endoplasmic reticulum; sarcolemma; nucleus; neuronal cell body membrane; neuronal cell body;
Biological process	visual learning; cellular response to steroid hormone stimulus; regulation of cardiac conduction; cardiac muscle contraction; sodium ion transport; cellular sodium ion homeostasis; adult locomotory behavior; sodium ion export across plasma membrane; cell communication by electrical coupling involved in cardiac conduction; response to glycoside; ion transport; memory; cellular potassium ion homeostasis; potassium ion transport; ion transmembrane transport; ionotropic glutamate receptor signaling pathway; transport; regulation of cardiac muscle cell membrane potential; establishment or maintenance of transmembrane electrochemical gradient; cerebral cortex development; cellular response to retinoic acid; cellular response to thyroid hormone stimulus; regulation of resting membrane potential; regulation of presynaptic membrane potential; cellular response to amyloid-beta; neuron projection maintenance; potassium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	478
	232975
	ENSG00000105409
	ENSMUSG00000040907
	P13637
	Q6PIC6
	NM_001256213; NM_001256214; NM_152296
	NM_001290469; NM_144921; NM_001374627
	NP_001243142; NP_001243143; NP_689509
	NP_001277398; NP_001361556
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium/potassium-transporting ATPase subunit alpha-3 is an enzyme that in humans is encoded by the ATP1A3 gene.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.