Aminolevulinic acid

δ-Aminolevulinic acid (also dALA, δ-ALA, 5ALA or 5-aminolevulinic acid), an endogenous non-proteinogenic amino acid, is the first compound in the porphyrin synthesis pathway, the pathway that leads to heme in mammals, as well as chlorophyll in plants.

δ-Aminolevulinic acid
Clinical data
Trade namesLevulan, NatuALA, Ameluz, others
Other names5-aminolevulinic acid
AHFS/Drugs.comMonograph
MedlinePlusa607062
License data
Routes of
administration
Topical, By mouth
ATC code
Legal status
Legal status
  • CA: ℞-only
  • US: ℞-only
  • EU: Rx-only
  • In general: ℞ (Prescription only)
Identifiers
  • 5-Amino-4-oxo-pentanoic acid
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.003.105
Chemical and physical data
FormulaC5H9NO3
Molar mass131.131 g·mol−1
3D model (JSmol)
Melting point118 °C (244 °F)
SMILES
  • O=C(CN)CCC(=O)O
  • InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9) Y
  • Key:ZGXJTSGNIOSYLO-UHFFFAOYSA-N Y
  (verify)

5ALA is used in photodynamic detection and surgery of cancer.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.