4-Aminophenylmercuric acetate

4-Aminophenylmercuric acetate (CH3CO2HgC6H4NH2, also known as 4-(Acetoxymercurio)aniline or APMA), is an organomercurial compound and thiol-blocking reagent used in experimental biology and chemistry to activate matrix metalloproteinases and collagenase proteolytic enzymes. The material is highly toxic.

4-Aminophenylmercuric acetate
Names
IUPAC name
Acetyloxy-(4-aminophenyl)mercury
Identifiers
3D model (JSmol)
3664749
ChemSpider
ECHA InfoCard 100.025.907
EC Number
  • 228-497-1
PubChem CID
  • InChI=1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1
    Key: RXSUFCOOZSGWSW-UHFFFAOYSA-M
SMILES
  • CC(=O)O[Hg]C1=CC=C(C=C1)N
Properties
C8H9HgNO2
Molar mass 351.757 g·mol−1
Appearance off-white powder
5 mM
Solubility DMSO
Hazards
GHS labelling:
Danger
H300, H310, H330, H373, H410
P260, P262, P264, P270, P271, P273, P280, P284, P301+P310, P302+P350, P304+P340, P310, P314, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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