21st Century Hits: Best of 2000–2012

21st Century Hits: Best of 2000–2012 is the fourth greatest hits compilation album by American country music artist Dwight Yoakam. It was released by New West Records on October 1, 2013. It includes songs from the albums Tomorrow's Sounds Today, Population Me, Blame the Vain, Dwight Sings Buck and 3 Pears, as well as a previously unreleased duet with Michelle Branch and a cover of "Crazy Little Thing Called Love" from his previous greatest hits collection, the 1999 Last Chance for a Thousand Years, that also appeared on the soundtrack to the 2006 film The Break-Up.