11-Deoxycorticosterone

11-Deoxycorticosterone
Names
	IUPAC name 21-Hydroxypregn-4-ene-3,20-dione
	Systematic IUPAC name (1S,3aS,3bS,9aR,9bS,11aS)-1-(Hydroxyacetyl)-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one
	Other names Deoxycorticosterone; Desoxycortone; Deoxycortone; Cortexone; 21-Hydroxyprogesterone; 21-Hydroxy-4-pregnene-3,20-dione; Reichstein's substance Q; Kendall's desoxy compound B; NSC-11319
Identifiers
CAS Number	64-85-7;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:16973;
ChEMBL	ChEMBL1498;
ChemSpider	5932;
ECHA InfoCard	100.000.543
IUPHAR/BPS	2871;
PubChem CID	6166;
UNII	40GP35YQ49;
CompTox Dashboard (EPA)	DTXSID0045254 ;
	InChI InChI=1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1 Key: ZESRJSPZRDMNHY-YFWFAHHUSA-N;
	SMILES O=C4\C=C2/[C@]([C@H]1CC[C@@]3([C@@H](C(=O)CO)CC[C@H]3[C@@H]1CC2)C)(C)CC4;
Properties
Chemical formula	C21H30O3
Molar mass	330.461 g/mol
Pharmacology
ATC code	H02AA03 (WHO)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone, and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. It is an active (Na+-retaining) mineralocorticoid. As its names indicate, 11-deoxycorticosterone can be understood as the 21-hydroxy-variant of progesterone or as the 11-deoxy-variant of corticosterone.

DOCA is the abbreviation for the ester 11-deoxycorticosterone acetate.

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