2022 Serbia Open – Singles

Andrey Rublev defeated Novak Djokovic in the final, 6–2, 6–7(4–7), 6–0 to win the singles tennis title at the 2022 Serbia Open.

Singles
2022 Serbia Open
Champion Andrey Rublev
Runner-up Novak Djokovic
Score6–2, 6–7(4–7), 6–0
Draw28 (4 Q / 3 WC )
Seeds8

Matteo Berrettini was the reigning champion, but chose not to defend his title.

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